High-density lipoprotein phospholipids interfere with dendritic cell Th1 functional maturation
نویسندگان
چکیده
منابع مشابه
High-density lipoprotein attenuates Th1 and th17 autoimmune responses by modulating dendritic cell maturation and function.
Aberrant levels and function of the potent anti-inflammatory high-density lipoprotein (HDL) and accelerated atherosclerosis have been reported in patients with autoimmune inflammatory diseases. Whether HDL affects the development of an autoimmune response remains elusive. In this study, we used apolipoprotein A-I-deficient (apoA-I(-/-)) mice, characterized by diminished circulating HDL levels, ...
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متن کاملDetermination of high-density lipoprotein phospholipids in serum.
I describe a method for measuring high-density lipoprotein phospholipids. Magnesium chloride and dextran sulfate are used to precipitate all low-density and very-low-density lipoproteins. The supernate contains only high-density lipoproteins, the phospholipid concentration of which is determined by an enzymic method. The precision of the method (CV) is 2.35% (10 repeated assays), and the mean v...
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ژورنال
عنوان ژورنال: Immunobiology
سال: 2012
ISSN: 0171-2985
DOI: 10.1016/j.imbio.2011.07.030